| Academy Award Nominations: |
| Best Adapted Screenplay: Shari Springer Berman and Robert Pulcini |
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| Golden Globe Nominations: |
| Best Supporting Actress: Hope Davis |
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| Other Awards: |
| Cannes Film Festival: FIPRESCI Prize (Un Certain Regard) |
| Sundance Film Festival: Grand Jury Prize (Dramatic) |
| Writers Guild of America: Best Adapted Screenplay |
| New York Film Critics Circle: Best Actress (Davis; also cited for The Secret Lives of Dentists); Best First Film |
| Los Angeles Film Critics Association: Best Picture; Best Screenplay |
| National Society of Film Critics: Best Picture; Best Screenplay |
| Boston Society of Film Critics: Best Screenplay |
| National Board of Review: Breakthrough Performance, Male (Giamatti); Special Mention for Excellence in Filmmaking |